Analysis of the co-operative interaction between the allosterically regulated proteins GK and GKRP using tryptophan fluorescence
Zelent B., Raimondo A., Barrett A., Buettger CW., Chen P., Gloyn AL., Matschinsky FM.
<jats:p>Using tryptophan fluorescence we explore in a unique way the co-operative interaction between two allosterically regulated proteins (GK and GKRP), which operate as a critical drug-sensitive molecular switch in hepatic carbohydrate metabolism.</jats:p>