Positions available

Applications are invited for a Senior Postdoctoral Research Scientist in Genomics of Sepsis at the University of Oxford. You will be based at the Centre for Human Genetics (CHG) within the group of Professor Julian Knight, joining an established team with a track record of innovation and high impact research in functional genomics and susceptibility to complex disease.

 

You will be responsible for analysing data arising from the programme including NGS, qPCR and RNA-seq data, as well as electronic health records. You will develop novel methodologies for analysis and data collection, informatics structures to manage large datasets, and machine learning models for patient stratification. You will be responsible for producing scientific reports and publications for high profile journals, including taking leadership in more specialised publications on novel aspects of bioinformatics. You will work as part of an interdisciplinary team involving close liaison with members of the Knight group, and collaborators in Danaher and Cepheid.You will also be responsible for creating, testing and using relevant computer code; maintaining and distributing completed software, and applying computational and statistical methodologies and algorithms.

 

It is essential that you hold a PhD/DPhil in Bioinformatics, Statistical Genetics, Statistics, Mathematics and Physics, Computer Science or a related discipline, and have a demonstrable interest in the research described here. You will have experience of computational genomics and/or bioinformatics together with functional genomic analysis. It is essential you have a strong publication record with evidence of a high level of self-motivation and ambition; experience of, and demonstrated competence in, scientific computing using at least one programming language, and excellent analytical and quantitative skills with a proven ability to think critically about scientific analysis in order to ensure robust results.

 

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

 

This position is offered full time on a fixed term contract until 30 September 2027 and is funded by the Danaher Corporation.

 

Only applications received before 12 midday on 17 September 2024 will be considered. Please quote 173607 on all correspondence.

We are seeking to appoint a Senior Postdoctoral Research Scientist in Severe Infection Genomics at the University of Oxford. You will be based at the Centre for Human Genetics (CHG) within the group of Professor Julian Knight, in an established team with a track record of innovation and high impact research in functional genomics and susceptibility to complex disease.

 

Your primary responsibility will be to analyse -omic and related multi-modal datasets for the human immune response, integrate with metagenomic data for the same patients providing high resolution pathogen profiling and help to develop the use of such data in patient care pathways and a multi-disciplinary team setting. You will support the development of appropriate research ethics approvals and processes for gaining appropriate research consent and data management to ensure relevant data generation and collection across several participating hospital sites. Other responsibilities include keeping detailed, accurate and comprehensible records of your work, and developing research questions within a specific context and conduct individual research.

 

It is essential that you hold a PhD/DPhil in Genetics, Genomics, Statistical Genetics, Bioinformatics, Statistics, Mathematics and Physics, Computer Science or a related discipline, along with some post qualification experience. You will have a demonstrable interest in the research described, research experience in genomics and experience in data management. Excellent analytical and quantitative skills with a proven ability to think critically about scientific analysis in order to ensure robust results is also essential for this role.

 

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

 

This position is offered full time on a fixed term contract until 1 September 2025 and is funded by the Barts Charity.

 

Only applications received before 12 midday on 7 October 2024 will be considered. Please quote 174588 on all correspondence.