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The skin microenvironment at the site of infection plays a role in the early events that determine protective T helper 1/type 1 immune responses during cutaneous leishmaniasis (CL) infection. During CL in nonhealing BALB/c mice, early interleukin-4 (IL-4) can instruct dendritic cells for protective Th1 immunity.

Original publication

DOI

10.1128/iai.00710-18

Type

Journal

Infection and Immunity

Publisher

American Society for Microbiology

Publication Date

12/2018

Volume

86