Our research targets infectious disease, autoimmunity, cardiovascular disease, mental health, cancer and inherited disease by understanding the underlying molecular drivers. This includes immune, inflammatory, metabolic and signaling processes, these fundamental pathways are shared across multiple diseases. This helps us to understand the drivers of human health and disease.
Latest publications
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CMV serostatus is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade
Milotay G. et al, (2025), Nature Medicine
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Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis
Sun B. et al, (2025), Science Advances, 11
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Saturation genome editing ofRNU4-2reveals distinct dominant and recessive neurodevelopmental disorders
De Jonghe J. et al, (2025)
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The value of large-scale programmes in human genomics
Horn R. et al, (2025), European Journal of Human Genetics