Toxic Cargoes Contributing to Dementia are Contained Within Extracellular Vesicles
17 January 2025
New research led by Dr Steph Fowler (UCL and now Oxford IMCM), Professor Karen Duff (UKDRI, UCL), with Dr Benjamin Ryskeldi-Falcon and Dr Tiana Behr (MRC LMB), have shed light on a potential pathway for the spread of harmful tau protein in Alzheimer's disease. Their findings, published in Nature Neuroscience, focus on structures called extracellular vesicles and their role in transporting toxic tau fragments.
New blood test could enable early detection of multiple cancers
8 January 2025
A new blood test – powered by machine learning – has shown real promise in detecting multiple types of cancer in their earliest stages, when the disease is hardest to detect. Developed by a team of researchers and co-lead by the Centre for Human Genetics’ Dr Dimitris Vavoulis, the test accurately detected six cancer types and could distinguish between people with and without cancer.
Professor Anneke Lucassen is the new Academic Champion for Public and Community Engagement with Research
9 December 2024
Anneke will chair the Public and Community Engagement with Research Advisory Board and launch our 2024-2029 strategy.
Dr Nicky Whiffin awarded Balfour Lecture 2025
25 November 2024
Nicky Whiffin, Associate Professor and Sir Henry Dale Fellow at the University of Oxford’s Big Data Institute and Centre for Human Genetics, has been awarded the 2025 Balfour Lecture by the Genetics Society.
Three new Oxford-GSK IMCM Fellows welcomed to the Centre for Human Genetics
18 November 2024
Last month the final two Oxford-GSK Institute of Molecular and Computational Medicine (IMCM) Fellows were welcomed to NDM’s Centre for Human Genetics. Dr Martina Hallegger and Dr Charmaine Lang join Dr Steph Fowler to build capacity in neurodegenerative disease research at the Centre.
DPhil student Grace Hood awarded Dr. Gregory D. Bossart Memorial One Health Scholarship 2024
13 November 2024
The $5000 Scholarship Award for 2024 was granted to Dr. Grace Hood for her One Health Project titled "Deforestation as a driver of emerging viral spillover events at the human-animal-environment interface in Malaysian Borneo"
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease
22 October 2024
A pioneering study published in Nature Immunology offers unprecedented insights into cellular responses to common treatments, paving the way to transform the treatment landscape for these chronic inflammatory conditions.
Possible new transmission route for highly pathogenic avian influenza
17 October 2024
A new study published in Nature Communications has identified a new potential transmission route for H5 highly pathogenic avian influenza viruses (HPAI). Understanding actual “bird flu” rates in humans will help prevent further spillover and a potential new pandemic.
DPhil Study into the cellular basis of Human Endometrial Cells could progress the development of therapeutics for endometriosis
16 October 2024
Magda Mareckova, a DPhil Student working with Prof Krina Zondervan, has created single-cell reference atlas of the human endometrium. The study was published in Nature Genetics.
New disease-inducing mechanism for inflammatory bowel disease (IBD) identified
11 September 2024
A study, published by the New England Journal of Medicine, has identified a new disease-inducing mechanism for inflammatory bowel disease (IBD) in which the immune system attacks its own regulatory function.