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Small Research Facilities

In addition to their research programmes, some of our core groups offer a range of scientific services to research groups in the Centre itself, in other University of Oxford departments, and in other institutions. In addition the Centre also provides free access to a number of databases and software applications.

Bioinformatics and Statistical Genetics

BSG provides advice and support in the following areas:

  • Advice on experimental design
  • Processing and analysis pipelines for NGS data (Illumina and ONT) and microarrays
  • Ensuring high data quality and providing QC reports
  • Extensive informatics support for tracking, processing and managing large volumes of raw sequence data
  • Training and advice on the use of a variety of bioinformatics tools and analyses
  • Collaborating with research groups to perform downstream analyses
  • Developing software tools to aid scientists in the analysis of omic datasets
  • Evaluating data from trials of cutting-edge technologies and methodologies (e.g. single-cell)
  • Assistance with manuscript preparation and submitting data to public repositories

Chromosome Dynamics

Chromosome Dynamics provides:

  • A range of different fluorescence in situ hybridization (FISH) applications
  • Related tissue culture techniques
  • Probe preparation
  • Support with cytological techniques, including Immunofluorescence and Chromogenic RNA in situ hybridization (ISH)

Cellular Imaging

Cellular Imaging provides:

  • State-of-the-art laboratories for fluorescence microscopy and spectroscopy with technical assistance in digital imaging and quantitative microscopy applied to live cells.
  • The Cellular Imaging Core performs research and development of cutting-edge fluorescence microscopy techniques. Lifetime Imaging, Fluorescence Correlation Spectroscopy and Super-Resolution microscopy approaches are available.
  • The Cellular Imaging Core also disseminates knowledge of fluorescence spectroscopic applications to the scientific community.

Biomedical Research Computing

Biomedical Research Computing provides a unified platform for biomedical research computing accessible to departments as well as to collaborators from around Oxford. Our services include:

  • High-performance batch (cluster) computing, including specialised hardware and software to support GPU-enabled code and AI/Machine Learning
  • Large, fast storage systems backed by ultra-fast networking
  • Low-cost data storage
  • On-premise cloud computing (OpenStack)
  • Training and workshops on using these facilities
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