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Found 13373 matches for

Common virus may improve skin cancer treatment outcomes

May is Skin Cancer Awareness Month, and a new study with input from researchers in the CHG has revealed that a common virus may positively influence how skin cancer patients respond to current treatments.

David Church awarded a Cancer Research UK Senior Cancer Research Fellowship

David Church received a Senior Cancer Research Fellowship from the Cancer Research UK Research Careers Committee to study MHC-I and MHC-II dysregulation in colorectal & endometrial cancer.

Study finds previously unidentified genetic determinants of rare disease

A landmark study involving researchers from the Centre for Human Genetics has identified 69 previously unidentified genetic determinants of rare disease, including uncommon forms of epilepsy and schizophrenia.

At-home test could play key role in type-1 diabetes screening

A new home test to diagnose type-1 diabetes (T1D) is being investigated in a major UK study led by researchers at the National Institute for Health and Care Research (NIHR) Oxford Biomedical Research Centre and NDM's Centre for Human Genetics.

Five Advance HE fellowships awarded to NDM teaching staff

Five members of the MSc Genomic Medicine teaching team have been awarded Advanced HE fellowships in recognition of their roles in teaching and supporting higher education learning.

Bowel cancer prediction test for IBD patients 90% accurate

Researchers in the CHG have authored a collaborative study which explored a new method for detecting bowel cancer, which was found to be more than 90% accurate at predicting which higher-risk people will develop this type of cancer in the future.

Oxford and GSK launch £50m programme to advance cancer research

Global biopharma company GSK invests up to £50 million in a collaboration with Oxford to advance the understanding of how cancer develops, which could inform future development of vaccines to prevent cancer.

Toxic Cargoes Contributing to Dementia are Contained Within Extracellular Vesicles

New research led by Dr Steph Fowler (UCL and now Oxford IMCM), Professor Karen Duff (UKDRI, UCL), with Dr Benjamin Ryskeldi-Falcon and Dr Tiana Behr (MRC LMB), have shed light on a potential pathway for the spread of harmful tau protein in Alzheimer's disease. Their findings, published in Nature Neuroscience, focus on structures called extracellular vesicles and their role in transporting toxic tau fragments.

New blood test could enable early detection of multiple cancers

A new blood test – powered by machine learning – has shown real promise in detecting multiple types of cancer in their earliest stages, when the disease is hardest to detect. Developed by a team of researchers and co-lead by the Centre for Human Genetics’ Dr Dimitris Vavoulis, the test accurately detected six cancer types and could distinguish between people with and without cancer.

Professor Anneke Lucassen is the new Academic Champion for Public and Community Engagement with Research

Anneke will chair the Public and Community Engagement with Research Advisory Board and launch our 2024-2029 strategy.

Dr Nicky Whiffin awarded Balfour Lecture 2025

Nicky Whiffin, Associate Professor and Sir Henry Dale Fellow at the University of Oxford’s Big Data Institute and Centre for Human Genetics, has been awarded the 2025 Balfour Lecture by the Genetics Society.

Three new Oxford-GSK IMCM Fellows welcomed to the Centre for Human Genetics

Last month the final two Oxford-GSK Institute of Molecular and Computational Medicine (IMCM) Fellows were welcomed to NDM’s Centre for Human Genetics. Dr Martina Hallegger and Dr Charmaine Lang join Dr Steph Fowler to build capacity in neurodegenerative disease research at the Centre.

DPhil student Grace Hood awarded Dr. Gregory D. Bossart Memorial One Health Scholarship 2024

The $5000 Scholarship Award for 2024 was granted to Dr. Grace Hood for her One Health Project titled "Deforestation as a driver of emerging viral spillover events at the human-animal-environment interface in Malaysian Borneo"

A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease

A pioneering study published in Nature Immunology offers unprecedented insights into cellular responses to common treatments, paving the way to transform the treatment landscape for these chronic inflammatory conditions.

Possible new transmission route for highly pathogenic avian influenza

A new study published in Nature Communications has identified a new potential transmission route for H5 highly pathogenic avian influenza viruses (HPAI). Understanding actual “bird flu” rates in humans will help prevent further spillover and a potential new pandemic.

DPhil Study into the cellular basis of Human Endometrial Cells could progress the development of therapeutics for endometriosis

Magda Mareckova, a DPhil Student working with Prof Krina Zondervan, has created single-cell reference atlas of the human endometrium. The study was published in Nature Genetics.

New disease-inducing mechanism for inflammatory bowel disease (IBD) identified

A study, published by the New England Journal of Medicine, has identified a new disease-inducing mechanism for inflammatory bowel disease (IBD) in which the immune system attacks its own regulatory function.

Developing the first cancer prevention vaccine for Lynch syndrome

Scientists from the Centre for Human Genetics at Nuffield Department of Medicine are taking the initial steps in developing the UK’s first vaccine to prevent cancer in people with Lynch syndrome, thanks to funding from Cancer Research UK.

New shingles vaccine could reduce risk of dementia

The new recombinant shingles vaccine ‘Shingrix’ is associated with a reduced risk of dementia compared to an earlier shingles vaccine, according to a major new study published in Nature Medicine.

New discovery renews hope for thousands with neurodevelopment disorders

A global collaboration led by scientists at the University of Oxford has discovered that genetic variants in a specific gene cause a rare neurodevelopmental disorder (NDD). NDD is a collective term for severe impairments in how the brain functions that impact learning, behaviour, speech, and movement. Most NDDs are thought to be genetic and caused by changes to DNA, however, to date, around 60% of individuals with these conditions do not know the specific DNA change that causes their disorder.

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