Contact information
Research groups
Gillian Douglas
PhD
Associate Professor of Cardiovascular Science
Large studies linking common variations to the occurrence of coronary artery disease have enabled us to identify several new genes that may have a causative influence on the susceptibility to developing coronary artery disease. However, for many of these genes the mechanism by which they alter cardiovascular disease pathology is unknown.
Recent publications
Inducible Endothelial Gch1 Deletion Reveals Rapid, Sex-Specific Effects on Blood Pressure and Pregnancy Outcomes
Journal article
Chuaiphichai S. et al, (2026), Hypertension, 83
An ALPK3 truncation variant causing autosomal dominant hypertrophic cardiomyopathy is partially rescued by mavacamten
Journal article
Leinhos L. et al, (2025), Scientific Reports, 15
Mutagenesis on a complex mouse genetic background by site-specific nucleases.
Journal article
Davies B. et al, (2024), Transgenic research, 33, 415 - 426
An ALPK3 truncation variant causing autosomal dominant hypertrophic cardiomyopathy is partially rescued by mavacamten
Preprint
Leinhos L. et al, (2024)
Hif-2α programs oxygen chemosensitivity in chromaffin cells
Journal article
Prange-Barczynska M. et al, (2024), Journal of Clinical Investigation, 134