Contact information
robin.choudhury@cardiov.ox.ac.uk
+44 (0)1865 234664
Miss Eunice Berry
eunice.berry@cardiov.ox.ac.uk
Colleges
Websites
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British Heart Foundation Alumni Reflections Series
Professor Choudhury interviewed by BHF Associate Medical Director Professor James Leiper
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Balliol College Lectures: A Cultural History through depictions of the Heart; Botticelli to Banksy
Professor Choudhury in discussion with Dr Jennifer Sliwka, Keeper of Western Art, Ashmolean Museum
The Beating Heart.
Robin Choudhury
MA DM FRCP
Professor of Cardiovascular Medicine
- Honorary Consultant Cardiologist
- Fellow in Biomedical Sciences, Balliol
Integrative Physiology (Systems Biology)
Overview
BACKGROUND:
Robin Choudhury qualified in medicine at the University of Oxford with postgraduate training in London (Royal Brompton & Hammersmith) and at Mount Sinai School of Medicine, New York. He is Professor of Cardiovascular Medicine at the University of Oxford; Consultant Cardiologist to the John Radcliffe Hospital and Research Fellow in Biomedical Sciences at Balliol. He is an Affiliated Researcher at the Institute of Regenerative Medicine.
He is co-PI of of the NovoNordisk Foundation supported Metabolite-related inflammation and disease (MeRIAD) consortium; Joint clinical lead in the MRC-BHF Centre of Research Excellence in Advanced Cardiac Therapies (REACT) and UK Chief Investigator for the ZEUS clinical trial of Ziltivekimab.
RESEARCH:
His translational science laboratory aims to understand how cells of the innate immune system are involved in processes of tissue homeostasis, injury and repair.
Areas of particular interest focus around: (1) understanding the role of monocytes, macrophages and neutrophils in acute myocardial infarction; myocardial regeneration vs repair and in atherosclerosis and (2) how bone marrow stem cells are 'programmed' e.g. by extracellular vesicles and through by genetic / epigenetic and metabolic mechanisms. The laboratory has a particular interest in hyperglycaemia-induced trained immunity.
CLINICAL PRACTICE:
Professor Choudhury has a specialist clinical interest in coronary artery disease and its management. He has particular expertise in the assessment and optimisation of cardiovascular risk factors and their interactions (e.g. cholesterol; diabetes; 'inflammation' and genetic risk).
Key publications
Inflammation reprogramming and immunomodulation: Next-generation treatments for atherosclerosis.
Journal article
Choudhury RP. et al, (2025), Cell reports. Medicine, 6
Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis
Journal article
Edgar L. et al, (2021), Circulation, 144, 961 - 982
Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair
Journal article
Simões FC. et al, (2020), Nature Communications, 11
Heart regeneration and repair after myocardial infarction: translational opportunities for novel therapeutics
Journal article
Cahill TJ. et al, (2017), Nature Reviews Drug Discovery, 16, 699 - 717
Inflammatory processes in cardiovascular disease: a route to targeted therapies
Journal article
Ruparelia N. et al, (2017), Nature Reviews Cardiology, 14, 133 - 144
Acute myocardial infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved transcriptional responses in mice and humans
Journal article
Ruparelia N. et al, (2015), European Heart Journal, 36, 1923 - 1934
Recent publications
Coronary Arteries Segmentation in Invasive X-ray Angiography: A Comprehensive Review and Benchmarking
Preprint
Lashgari M. et al, (2026)
Plasma extracellular vesicle modulate immune cell transcriptional responses following acute myocardial infarction.
Journal article
Timms L. et al, (2026), iScience, 29
HDL Regulates TGFβ-Receptor Lipid Raft Partitioning, Restoring Contractile Features of Cholesterol-Loaded Vascular Smooth Muscle Cells.
Journal article
Nagesh PT. et al, (2026), JACC. Basic to translational science, 11
Trained Immunity and Cardiovascular Risk: An Immunological Perspective.
Journal article
Boden KA. et al, (2026), Immunological reviews, 337
Endothelial thrombomodulin-Its role in trauma-induced coagulopathy.
Journal article
Abu-Hanna J. et al, (2026), Transfusion
A novel in vitro model of trauma-induced endotheliopathy provides a platform for studying mechanisms of coagulopathy
Journal article
Abu-Hanna J. et al, (2025), Blood Vessels, Thrombosis & Hemostasis, 2, 100087 - 100087
The Beating Heart: art meets science in the story of the heart.
Journal article
Choudhury RP., (2025), Cardiovascular research, 121, 1972 - 1974
Cardiac lymphatics retain LYVE-1-dependent macrophages during neonatal mouse heart regeneration
Journal article
Chapman BG. et al, (2025), Nature Cardiovascular Research, 4, 1258 - 1276
Inflammation reprogramming and immunomodulation: Next-generation treatments for atherosclerosis.
Journal article
Choudhury RP. et al, (2025), Cell reports. Medicine, 6
Stabilisation of HIF signalling extends epicardial activation and neonatal heart regeneration
Preprint
Gamen E. et al, (2025)