Contact information
Cellular Imaging Core Facility Webpage
Centre for Human Genetics, University of Oxford
James Bancroft
PhD
Cellular Imaging Core Facility Head & NDM SRF Network Lead
I am Head of the Cellular Imaging Core Facility (CICF) at the Centre for Human Genetics, where I lead a team of three specialists supporting a diverse research community. We work closely with researchers to design, execute and analyse imaging assays across a wide range of biological systems, from cells and organoids through to tissues and whole organisms.
Since taking on this role, I have focused on expanding both the technological and analytical capabilities of the CICF. Through successful grant applications and strategic industry partnerships, I have helped to bring cutting-edge imaging platforms and analysis workflows into the department, ensuring that our users can tackle increasingly complex biological questions with confidence.
My background is in advanced imaging assay development, and I am an expert in multiple microscopy modalities, combining experience from both academia and industry. Before joining the CICF, I spent over three years working in industry at the forefront of microscopy innovation, and six years as a post-doctoral researcher at the University of Oxford, where I used live-cell imaging to investigate how cell division is regulated. I particularly enjoy collaborating with researchers to turn challenging imaging ideas into robust, quantitative experiments.
In addition to leading the CICF, I play an active role in the wider Small Research Facility network within the Nuffield Department of Medicine, helping to foster collaboration and sustainable access to advanced technologies.
Recent publications
Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis
Journal article
Sun B. et al, (2025), Science Advances, 11
A Novel Macrophage Subpopulation Conveys Increased Genetic Risk of Coronary Artery Disease.
Journal article
Jiang J. et al, (2024), Circulation research, 135, 6 - 25
Stem-cell derived neurosphere assay highlights the effects of viral infection on human cortical development
Journal article
Drydale E. et al, (2024), Brain, Behavior, and Immunity, 115, 718 - 726
CRISPR/Cas9-mediated knockout of IL1RAPL1 in stem cells highlights a role in neural cell migration during cortical development
Preprint
Holden K. et al, (2022)
PP1 promotes cyclin B destruction and the metaphase-anaphase transition by dephosphorylating CDC20.
Journal article
Bancroft J. et al, (2020), Molecular biology of the cell, 31, 2315 - 2330