Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Accept all cookies Reject all non-essential cookies Find out more

Taylor group: Translational Genomics

Logo

Translation of genetics research into clinical practice

Research overview

Oxford Biomedical Research Centre – Genomic Medicine Theme

Jenny Taylor

Professor Jenny Taylor is Co-Theme Leader of the Genomic Medicine Theme of the Oxford Biomedical Research Centre (BRC), one of several such centres in the UK funded by the National Institute of Health Research with the overarching aim of translating advances in biomedical research into NHS practice.

The aims of the Genomic Medicine Theme are to:

  • apply next-generation sequencing technologies (NGS) to the discovery of novel disease genes
  • evaluate and develop these technologies for rapid translation into the clinic, resulting in new NHS-based genetics services
  • provide genetics and genomics infrastructure (platforms and expertise) to support other translational research projects

Our research is truly multi-disciplinary, integrating researchers and clinicians (particularly those based at the Centre) from a range of medical specialities, with clinical scientists from the diagnostic laboratories, and others, including specialists in health economics, informatics, and ethics.

The activities of the Genomic Medicine Theme are divided into three sub-themes, each with a specific programme of collaborative projects.  Members of the Taylor group are involved across all three sub-themes, either running projects of their own or as collaborators in wider programmes.

Clinical applications of sequencing

Mechanisms to biomarkers

Technology translation

Our team

Selected publications

Latest publications

CMS subtypes correlate with complete response in trial of neoadjuvant Galunisertib plus chemoradiation in rectal cancer

Journal article

Rajamanickam V. et al, (2026), Translational Oncology, 66, 102690 - 102690

ESR1 Mutation in Endocrine Treatment-Naïve Endometrial Cancer: Prevalence, Characteristics, and Prognostic Implications, Results from the UTOLA Phase II GINECO Trial

Journal article

Blanc-Durand F. et al, (2026), Clinical Cancer Research, 32, 963 - 969

Supplementary Table S1 from ESR1 Mutation in Endocrine Treatment-Naïve Endometrial Cancer: Prevalence, Characteristics, and Prognostic Implications, Results from the UTOLA Phase II GINECO Trial

Other

Blanc-Durand F. et al, (2026)

Data from ESR1 Mutation in Endocrine Treatment-Naïve Endometrial Cancer: Prevalence, Characteristics, and Prognostic Implications, Results from the UTOLA Phase II GINECO Trial

Other

Blanc-Durand F. et al, (2026)

British Society of Gastroenterology guidelines on colorectal surveillance in inflammatory bowel disease

Journal article

East JE. et al, (2026), Gut, 75, 442 - 475

The Role of Fibroblast–Epithelial Cross-Talk on the Distribution of Distinct Fibroblast Phenotypes in the Intestinal Crypt

Journal article

Atkinson G. et al, (2026), Bulletin of Mathematical Biology, 88

Severe necrotizing soft tissue infections (SENSEI) study: Protocol for a multi-centered audit

Journal article

Yoshimura R. et al, (2026), JPRAS Open, 48, 331 - 336

Changes in absolute coronary blood flow and myocardial resistance after percutaneous coronary intervention.

Journal article

Marin F. et al, (2026), EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 22, e301 - e312

Expanding the genotypic spectrum of combined oxidative phosphorylation deficiency 54.

Journal article

Lai KL. et al, (2026), Neurogenetics, 27

TCR T cells targeting IgA- and IgG-expressing multiple myeloma.

Journal article

Douvlataniotis K. et al, (2026), Blood

Related research themes

Translational genetics