Dr Justin P. Whalley
Senior Bioinformatician
Dr Justin P. Whalley is currently (2023) a member of the faculty of the Chicago Medical School at Rosalind Franklin University of Medicine and Science.
He was a senior bioinformatician in the Knight Group from 2017 to 2022 and Research Member of Common Room at Kellogg College. He was the lead for the Extreme Response Functional Genomics project, as well as the head of Integration (Tensors) working group for the COVID-19 Multi-omic Blood Atlas (COMBAT).
Publications from his time in the group concentrated on immunity and the host response to infection. This included work on CRISPR/Cas9, epigenetics, long read technologies, tensor decomposition and imputation.
His teaching responsibilities included the Introduction to Statistics module to first year DPhil in Genomic Medicine and Statistics students, and the Data Science in Python module to the Masters in Modelling for Global Health students.
He was heavily involved in public engagement and led the group that won the Wellcome Centre for Human Genetics "Excellence in Public Engagement for Projects" 2019 prize.
Recent publications
-
Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
Journal article
Zhang P. et al, (2022), Genome Biology, 23
-
Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity
Journal article
Gilchrist JJ. et al, (2022), Nature Communications, 13
-
High-throughput mass spectrometry maps the sepsis plasma proteome and differences in response
Preprint
Mi Y. et al, (2022)
-
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
Journal article
Ahern DJ. et al, (2022), Cell, 185, 916 - 938.e58
-
Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages
Journal article
Navarro-Guerrero E. et al, (2021), Scientific Reports, 11
-
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
Working paper
Ahern DJ. et al, (2021)
-
Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity
Journal article
Gilchrist JJ. et al, (2021)
-
Using de novo assembly to identify structural variation of complex immune system gene regions
Journal article
Zhang J-Y. et al, (2021)
-
Framework for quality assessment of whole genome cancer sequences
Journal article
Whalley JP. et al, (2020), Nature Communications, 11
-
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
Journal article
Bailey MH. et al, (2020), Nature Communications, 11