Colleges
Oxford Postgraduate Teaching Network
The OPTN brings together academic and learning support staff involved in postgraduate taught programmes to share good practice, and provide resources and support for course design, teaching, delivery and assessment methods.
Delia O'Rourke
PhD SFHEA
Co Director, MSc in Genomic Medicine
Education and Curriculum
As Co-Director of the MSc in Genomic Medicine, I lead curriculum development, educational innovation and support teaching staff in their educational development and training. My work focuses on enhancing teaching through evidence-based pedagogical approaches, with particular emphasis on active learning methodologies, digitally supported inclusive teaching practices, universal design for learning principles and discipline-specific educational research. To this end, I set up a community of practice dedicated to sharing expertise and innovation in postgraduate teaching and learning, the Oxford Postgraduate Teaching Network (OPTN), with Tracy Bye in 2021. The OPTN's success was recognised with a Teaching Excellence Project award from the Medical Sciences Division in 2022.
My research career spans molecular biology, genetics, and host-pathogen interactions across multiple model organisms. After receiving my undergraduate degree in Biochemistry and PhD in Virology from the University of London, I pursued a research at Harvard Medical School working with Saccharomyces cerevisiae. I subsequently joined Professor Doug Higgs' laboratory at the Weatherall Institute of Molecular Medicine, Oxford, investigating the role of ATR-X protein in alpha-globin gene regulation. My later research focused on C. elegans in collaboration with Professor Jonathan Hodgkin at the Department of Biochemistry where we explored host:pathogen interactions through genetic, biochemical, and 'omic' approaches, with particular attention to the nematode surface coat.
In 2017, I transitioned to focus on educational development, serving as an Educational Development Consultant at the Centre for Teaching and Learning at Oxford. In this role, I designed and implemented online and in-person training programmes for STEM educators in higher education. This experience led to my role as Co-Director for the MSc in Genomic Medicine at the Nuffield Department of Medicine in 2022.
My current research interests combine my scientific background with educational innovation. I collaborate with colleagues across Oxford and beyond to investigate the effectiveness of digital educational tools in postgraduate education, with a particular focus on enhancing teaching and learning in genomic medicine and related fields.
Recent publications
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Mutations of <i>nhr-49</i> affect <i>C. elegans</i> susceptibility to <i>Yersinia</i> biofilms.
Hodgkin J. et al, (2025), microPublication biology, 2025
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Isolation and molecular identification of nematode surface mutants with resistance to bacterial pathogens.
O'Rourke D. et al, (2023), G3 (Bethesda, Md.), 13
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Lipodisqs for eukaryote lipidomics with retention of viability: Sensitivity and resistance to Leucobacter infection linked to C.elegans cuticle composition.
Bada Juarez JF. et al, (2019), Chemistry and physics of lipids, 222, 51 - 58
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Cuticle Integrity and Biogenic Amine Synthesis in Caenorhabditis elegans Require the Cofactor Tetrahydrobiopterin (BH4)
Loer CM. et al, (2015), Genetics, 200, 237 - 253
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Caenorhabditis elegans Bacterial Pathogen Resistant bus-4 Mutants Produce Altered Mucins
Parsons LM. et al, (2014), PLoS ONE, 9, e107250 - e107250
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Glycosylation Genes Expressed in Seam Cells Determine Complex Surface Properties and Bacterial Adhesion to the Cuticle of Caenorhabditis elegans
Gravato-Nobre MJ. et al, (2011), Genetics, 187, 141 - 155
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The Core-1 O-glycans of Microbacterium nematophilum Resistant Caenorhabditis elegans bus-4 mutants are altered
Rahman M. et al, (2011), FASEB JOURNAL, 25