Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Head of Computational Genomics Group

Head of Computational Genomics Group

Matthieu Miossec


Head of Computational Genomics Group

  • Head of CGG since March 2024
  • Prev. Senior Bioinformatician and acting Deputy Manager
  • MSc module lead for Genomic Medicine

Computational Genomics Group

Member of the (f. Wellcome) Centre's Bioinformatics Core since September 2020 with a full decade of bioinformatics and programming experience which encompasses whole-exome sequencing (particularly in relation to congenital heart disease), metagenomics and a recent growing amount of RNA sequencing. Happy to help with all your bioinformatics and Python-related queries in your language of choice: English, French or Spanish. I also provide teaching and training in whole exome/genome sequencing topics, Python and WDL, with plans to expand into machine learning.

I have some recent experience performing genomics in the cloud, using Google Cloud and the Broad Institute's genomics platform Terra. I have adopted the platform's workflow language of choice, WDL, for both cloud and HPC work. In 2018, I collaborated with the GATK dev team on a case study based on previous PhD/RA work which can be found here: reproducibility case study on Terra (see also chapter 14 of Genomics in the Cloud by Geraldine Van der Auwera & Brian O'Connor).

I am currently exploring metabolomics and machine learning. Happy to start receiving questions about either.


I earned a BSc in Computer Science from Durham University and an MSc in Bioinformatics and Computational Systems Biology from the University of Newcastle-Upon-Tyne. With support from the British Heart Foundation, I formally entered the field of genomic medicine in 2012, working at the Institute of Genetic Medicine in Newcastle, where I earned my PhD in 2016. My main focus was uncovering rare genetic variants predisposing to congenital heart diseases, such as Tetralogy of Fallot, using whole-exome sequencing data. After briefly working as a research associate at the Institute, I moved to Chile and joined the Centre for Bioinformatics and Integrative Biology (CBIB) where I delved into the world of metagenomics. During this time, I developed a growing passion for machine learning and gained a MOOC certificate on the subject.

Key publications

Recent publications

More publications