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The authors present a retrospective study of 120 cases of epidermoid carcinoma of the esophagus, in which they proposed to investigate the etiopathogenic relation between gastroesophageal reflux and noplastic development. A statistically significant relation was found between esophagitis and cancer of the distal esophageal third, indicating the need for vigilance of patients with reflux and for randomized prospective studies to clarify the problem definitively.


Journal article


Revista espanola de las enfermedades del aparato digestivo

Publication Date





164 - 166


Humans, Carcinoma, Squamous Cell, Esophageal Neoplasms, Esophagitis, Peptic, Hernia, Hiatal, Retrospective Studies, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male