Molecular Epidemiology of Clostridium difficile Strains in Children Compared with That of Strains Circulating in Adults with Clostridium difficile-Associated Infection
Stoesser N., Crook DW., Fung R., Griffiths D., Harding RM., Kachrimanidou M., Keshav S., Peto TE., Vaughan A., Walker AS., Dingle KE.
ABSTRACT Molecular analysis of Clostridium difficile (28 isolates) from children ( n = 128) in Oxfordshire, United Kingdom, identified eight toxigenic genotypes. Six of these were isolated from 27% of concurrent adult C. difficile -associated infections studied ( n = 83). No children carried hypervirulent PCR ribotype 027. Children could participate in the transmission of some adult disease-causing genotypes.