Please mind the gap: Axonal transport deficits in multiple sclerosis neurodegeneration
Dendrou CA., Fugger L.
© 2014 Elsevier Inc. In this issue, Sorbara etal. (2014) demonstrate that axonal transport impairment is an early feature of neurodegeneration in multiple sclerosis models. This transport deficit is reversible by anti-inflammatory intervention but, if untreated, can contribute to late-stage axonal dystrophy. In this issue Sorbara etal. (2014) demonstrate that axonal transport impairment is an early feature of neurodegeneration in multiple sclerosis models. This transport deficit is reversible by anti-inflammatory intervention but, if untreated, can contribute to late-stage axonal dystrophy.