Bayesian methods for statistical reconstruction of haplotypes
Donnelly P.
© Springer-Verlag Berlin Heidelberg 2004. The talk will describe the general issues in Bayesian approaches to haplotype reconstruction, including the distinction between choice of prior distribution, and the computational methods used to approximate posterior distributions. We describe recent improvements to the software PHASE, including handling missing data and improved computational methods, and compare its behaviour to some other published methods.