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Data from different individuals at a single locus are positively correlated because of the shared genealogy of the sampled genes. This paper illustrates the qualitative effects on genealogical trees of assumptions about population demography, and it considers the consequences for genetic variability. An understanding of these effects is invaluable in the interpretation of data and for inferences about population history. In contrast, traditional genetic measures of diversity and approximation methods do not seem well suited for addressing the problem.

Original publication

DOI

10.1002/9780470514887.ch3

Type

Journal article

Journal

Ciba Foundation symposium

Publication Date

01/1996

Volume

197

Pages

25 - 40

Addresses

Department of Statistics, University of Chicago, IL 60637, USA.

Keywords

Animals, Humans, Evolution, Molecular, Phylogeny, Genome, Human, Genetic Variation