Molecular mechanism of BMP signal control by Twisted gastrulation
Malinauskas T. et al, (2024), Nature Communications, 15
Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis
Brown M. et al, (2023), EMBO Molecular Medicine
Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features
Flanagan DJ. et al, (2023), Nature Communications, 14
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features
Flanagan DJ. et al, (2022), Nature Communications, 13
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Vasquez EG. et al, (2022), Cell stem cell, 29, 1213 - 1228.e8
BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration
Koppens MAJ. et al, (2021)
Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification
Kleeman SO. et al, (2020), Gut, 69, 1092 - 1103
The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression.
Thomas R. et al, (2019), Scientific reports, 9
Evolutionary history of human colitis-associated colorectal cancer
Baker A-M. et al, (2019), Gut, 68, 985 - 995
The evolutionary landscape of colorectal tumorigenesis
Cross W. et al, (2018), Nature Ecology & Evolution, 2, 1661 - 1672
Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer
Irshad S. et al, (2017), The Journal of Pathology, 242, 178 - 192
Regulation of BRAF protein stability by a negative feedback loop involving the MEK–ERK pathway but not the FBXW7 tumour suppressor
Hernandez MA. et al, (2016), Cellular Signalling, 28, 561 - 571
Mechanisms of action of bone morphogenetic proteins in cancer
Davis H. et al, (2016), Cytokine & Growth Factor Reviews, 27, 81 - 92
Microenvironmental control of stem cell fate in intestinal homeostasis and disease
Biswas S. et al, (2015), The Journal of Pathology, 237, 135 - 145
Microenvironmental control of stem cell fate in intestinal homeostasis and disease
Biswas S. et al, (2015), Journal of Pathology, 237, 135 - 145
Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche
Davis H. et al, (2015), Nature Medicine, 21, 62 - 70
A Polymorphic Enhancer near GREM1 Influences Bowel Cancer Risk through Differential CDX2 and TCF7L2 Binding
Lewis A. et al, (2014), Cell Reports, 8, 983 - 990
Aberrant Epithelial GREM1 Expression Promotes Stem-Cell Plasticity and Ectopic Crypt Formation in the Pathogenesis of Familial and Sporadic Human Polyps
Davis HL. et al, (2014), GASTROENTEROLOGY, 146, S86 - S86