Structural insights into Frizzled3 through nanobody modulators.
Hillier J. et al, (2024), Nat Commun, 15
Improving the representativeness of UK’s national COVID-19 Infection Survey through spatio-temporal regression and post-stratification
Pouwels KB. et al, (2024), Nature Communications, 15
Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain
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Publisher Correction: Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells.
Barnkob MB. et al, (2024), Nat Commun, 15
Semmaphorin 3 A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells.
Barnkob MB. et al, (2024), Nat Commun, 15
Structure and function of Semaphorin-5A glycosaminoglycan interactions
Nagy GN. et al, (2024), Nature Communications, 15
Structural insights into Frizzled assembly by acylated Wnt and Frizzled Connector domain
Chang T-H. et al, (2022)
Structural Analysis and Development of Notum Fragment Screening Hits.
Zhao Y. et al, (2022), ACS chemical neuroscience
Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes
Walters LC. et al, (2022), Cell Reports, 39
The guidance and adhesion protein FLRT2 dimerizes in cis via dual small-X3-small transmembrane motifs.
Jackson V. et al, (2022), Structure (London, England : 1993)
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.
Willis NJ. et al, (2022), Journal of medicinal chemistry
Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity
Li D. et al, (2022), Communications Biology, 5
Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity
Steadman D. et al, (2021), Journal of Medicinal Chemistry
Quantitative SARS-CoV-2 anti-spike responses to Pfizer–BioNTech and Oxford–AstraZeneca vaccines by previous infection status
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NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.
Flanagan DJ. et al, (2021), Nature, 594, 430 - 435
Small-molecule inhibitors of carboxylesterase Notum
Zhao Y. et al, (2021), Future Medicinal Chemistry
Caffeine inhibits Notum activity by binding at the catalytic pocket
Zhao Y. et al, (2020), Communications Biology, 3