Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1.
Beach C. et al, (2023), The Journal of clinical investigation, 133
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Vasquez EG. et al, (2022), Cell stem cell, 29, 1213 - 1228.e8
Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma.
Nijhuis A. et al, (2022), Nat Commun, 13
BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration
Koppens MAJ. et al, (2021)
Tracing Nutrient Flux Following Monocarboxylate Transporter-1 Inhibition with AZD3965.
Braga M. et al, (2020), Cancers, 12
The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro.
Sborchia M. et al, (2019), Archives of toxicology, 93, 3345 - 3366
The 14q32 maternally imprinted locus is a major source of longitudinally stable circulating microRNAs as measured by small RNA sequencing.
Valbuena GN. et al, (2019), Scientific reports, 9
The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation.
Parzych K. et al, (2019), Oncogene, 38, 3216 - 3231
Spinal Cord Metabolic Signatures in Models of Fast- and Slow-Progressing SOD1G93A Amyotrophic Lateral Sclerosis.
Valbuena GN. et al, (2019), Frontiers in neuroscience, 13
Altered Metabolic Profiles Associate with Toxicity in SOD1G93A Astrocyte-Neuron Co-Cultures.
Valbuena GN. et al, (2017), Scientific reports, 7
Suppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion.
Koufaris C. et al, (2016), Journal of proteome research, 15, 2618 - 2625
Metabolomic Analysis Reveals Increased Aerobic Glycolysis and Amino Acid Deficit in a Cellular Model of Amyotrophic Lateral Sclerosis.
Valbuena GN. et al, (2016), Molecular neurobiology, 53, 2222 - 2240
Systematic integration of molecular profiles identifies miR-22 as a regulator of lipid and folate metabolism in breast cancer cells.
Koufaris C. et al, (2016), Oncogene, 35, 2766 - 2776
Inadequate fine-tuning of protein synthesis and failure of amino acid homeostasis following inhibition of the ATPase VCP/p97.
Parzych K. et al, (2015), Cell death & disease, 6
Profiling the metabolic signature of senescence.
Geier FM. et al, (2013), Methods in molecular biology (Clifton, N.J.), 965, 355 - 371