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Publications

Cytomegalovirus infection protects against metastatic melanoma and modulates oncological outcome and toxicity to checkpoint immunotherapy

Milotay G. et al, (2024)

An isoform quantitative trait locus in SBNO2 links genetic susceptibility to Crohn's disease with defective antimicrobial activity.

Aschenbrenner D. et al, (2024), Nature communications, 15

Characterization of the genetic determinants of context-specific DNA methylation in primary monocytes.

Gilchrist JJ. et al, (2024), Cell genomics, 4

Demultiplexing of single-cell RNA-sequencing data using interindividual variation in gene expression

Nassiri I. et al, (2024), Bioinformatics Advances, 4

Peripheral monocyte transcriptomics associated with immune checkpoint blockade outcomes in metastatic melanoma

Cooper R. et al, (2024)

A role for SETD2 loss in tumorigenesis through DNA methylation dysregulation.

Javaid H. et al, (2023), BMC cancer, 23

scQCEA: a framework for annotation and quality control report of single-cell RNA-sequencing data.

Nassiri I. et al, (2023), BMC genomics, 24

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Pairo-Castineira E. et al, (2023), Nature, 617, 764 - 768

Characterisation of the genetic determinants of context specific DNA methylation in primary monocytes

Gilchrist JJ. et al, (2023)

Deep sequencing of the T cell Receptor reveals common and reproducible CD8+signatures of response to checkpoint immunotherapy

Watson RA. et al, (2023)

IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma

Taylor CA. et al, (2022), Nature Medicine, 28, 2592 - 2600

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Ahern DJ. et al, (2022), Cell, 185, 916 - 938.e58

An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Peng Y. et al, (2022), Nature Immunology, 23, 50 - 61

Immune checkpoint blockade sensitivity and progression-free survival associates with baseline CD8 + T cell clone size and cytotoxicity

Watson RA. et al, (2021), Science Immunology, 6

Interferon-Gamma–Producing CD8+ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor–Colitis

Sasson SC. et al, (2021), Gastroenterology, 161, 1229 - 1244.e9

Immunodominant NP105-113-B*0702 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Dong T. et al, (2021)

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Ahern DJ. et al, (2021)

EPISPOT: an epigenome-driven approach for detecting and interpreting hotspots in molecular QTL studies

Ruffieux H. et al, (2020)

Sensitivity to Immune Checkpoint Blockade and Progression-Free Survival is associated with baseline CD8+T cell clone size and cytotoxicity

Watson RA. et al, (2020)