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Publications

DNA methylation of insulin signaling pathways is associated with HOMA2-IR in primary myoblasts from older adults.

Burton MA. et al, (2023), Skeletal muscle, 13

European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.

Budu-Aggrey A. et al, (2023), Nature communications, 14

Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance.

Amarasinghe HE. et al, (2023), BMC genomics, 24

Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.

van Amstel RBE. et al, (2023), Intensive care medicine

SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses

Wellington D. et al, (2023), Heliyon, e20076 - e20076

Vaccine-induced CD8+ T cells are key to protection from SARS-CoV-2.

Antoun E. et al, (2023), Nature immunology

A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology.

Akbari P. et al, (2023), Nature communications, 14

A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery.

Torrance HD. et al, (2023), Annals of surgery

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.

Pairo-Castineira E. et al, (2023), Nature, 619

SARS-CoV-2 human challenge reveals single-gene blood transcriptional biomarkers that discriminate early and late phases of acute respiratory viral infections

Rosenheim J. et al, (2023)

Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis

Brown AC. et al, (2023), Cell Genomics, 3, 100306 - 100306

Genomic hallmarks and therapeutic implications of G0 cell cycle arrest in cancer.

Wiecek AJ. et al, (2023), Genome biology, 24

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.

Pairo-Castineira E. et al, (2023), Nature

Persistence of inflammatory and vascular mediators 5 months after hospitalization with COVID-19 infection

Melhorn J. et al, (2023), Frontiers in Medicine, 10

Chromosome conformation capture approaches to investigate 3D genome architecture in Ankylosing Spondylitis

Davidson C. et al, (2023), Frontiers in Genetics, 14

A transcriptomic approach to understand patient susceptibility to pneumonia after abdominal surgery

Torrance H. et al, (2023)

BurkHostGEN: a study protocol for evaluating variations in the Burkholderia pseudomallei and host genomes associated with melioidosis infection.

Angchagun K. et al, (2023), Wellcome open research, 8

Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection

Mentzer AJ. et al, (2023), Nature Medicine, 29, 147 - 157

Erratum: Transcriptomic Signatures in Sepsis and a Differential Response to Steroids. From the VANISH Randomized Trial (American Journal of Respiratory and Critical Care Medicine (2019) 199 (980–986) DOI: 10.1164/rccm.201807-1419OC)

Antcliffe DB. et al, (2022), American Journal of Respiratory and Critical Care Medicine, 206, 1572 - 1573

Association between age and the host response in critically ill patients with sepsis.

Michels EHA. et al, (2022), Critical care (London, England), 26

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