Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

MBiochem Final year student

Gene expression in sepsis

mark-photo-2.pngAs part of my MBiochem degree, I am undertaking a research project looking studying the changes in monocyte gene expression in sepsis. Sepsis is abnormal inflammatory response in response to severe infection. Sepsis mortality is currently between 25% and 50%. A Previous eQTL analysis has identified eQTLs related to sepsis. We measuring gene expression of LPS-stimulated human monocytes with RT-qPCR in order to validate those eQTLs. We also using RT-qPCR to measure the inflammatory response of monocytes by quantifying the expression of pro- and anti-inflammatory cytokines. We aim to use this information to help characterise the pathology of sepsis.

I am currently studying for an undergraduate MBiochem degree at the University of Oxford. I have previously researched the development of the GABA pathway in developing chicken brain in the Dept. of physiology, anatomy and genetics at University of Oxford.