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Much of modern biomedical research involves collecting and analysing large-scale data sets on biological variation. The Statistical and Population Genetics programme aims to use statistical analysis and mathematical modelling to describe and understand patterns of biological variation. Group members have played key roles in major international initiatives including the Wellcome Trust Case Control Consortia (WTCCC, WTCCC2), the 1000 Genomes Project and the International HapMap Project. (Peter Donnelly, Zamin IqbalGerton LunterGil McVean, Andrew Morris, Simon Myers, Chris Spencer, Christopher Yau)