Avigail Taylor
MEng, DPhil
Technical Lead in Bioinformatics at the Institute of Molecular and Computational Medicine
I joined the Institute of Molecular and Computational Medicine as Technical Lead in Bioinformatics in April 2023. In this role, I lead the bioinformatics and computational biology efforts of Oxford-based IMCM bioinformaticians and other researchers undertaking computational work. I also conduct hands-on bioinformatics work myself, developing and implementing methods for the analysis of novel data types, and building workflows to align analyses across the different IMCM projects.
I am a bioinformatician, computational biologist and software engineer, with an MEng in Computing from Imperial College London, and a DPhil in Bioinformatics from the University of Oxford. Prior to joining the IMCM, I was Deputy Manager of the Bioinformatics Core Facility at the Wellcome Centre for Human Genetics, and, before that, I held postdoctoral positions at the University of Oxford and the Medical Research Council. In these positions, I contributed to projects spanning the whole bioinformatics process, from conducting the primary analyses of raw experimental data, to developing and employing downstream, higher-level computational methods for contextualising, integrating and interpreting functional genomics experimental results.
My DPhil was in mouse genomic variation, however I moved into human disease with my second postdoctoral position, and have since been involved in a variety of research areas, including ADHD, prostate cancer and cardiovascular diseases.
Recent publications
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GeneFEAST: the pivotal, gene-centric step in functional enrichment
analysis interpretation
Preprint
Taylor A. et al, (2023)
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Gene Networks Underlying Convergent and Pleiotropic Phenotypes in a Large and Systematically-Phenotyped Cohort with Heterogeneous Developmental Disorders
Journal article
Andrews T. et al, (2015), PLOS Genetics, 11, e1005012 - e1005012
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Duplications in ADHD patients harbour neurobehavioural genes that are co‐expressed with genes associated with hyperactivity in the mouse
Journal article
Taylor A. et al, (2015), American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 168, 97 - 107
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GeneNet Toolbox for MATLAB: a flexible platform for the analysis of gene connectivity in biological networks
Journal article
Taylor A. et al, (2015), Bioinformatics, 31, 442 - 444
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The genomic landscape shaped by selection on transposable elements across 18 mouse strains
Journal article
Nellåker C. et al, (2012), Genome Biology, 13, R45 - R45