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Hayley Belnoue-Davis

Senior post-doctoral researcher and lab manager


Research summary

I am currently working on CRUK funded programme “Stem cells and adaptive molecular phenotype in colorectal cancer (STAMP-CRC)” which seeks to explore the impact of therapeutic selective pressures on stem cell molecular phenotype and target the pathways that enable the rapid evolution of drug resistance.

Recent publications

Gil Vazquez E, Nasreddin N, Valbuena GN, Mulholland EJ, Belnoue-Davis HL, Eggington HR, Schenck RO, Wouters VM, Wirapati P, Gilroy K, Lannagan TRM, Flanagan DJ, Najumudeen AK, Omwenga S, McCorry AMB, Easton A, Koelzer VH, East JE, Morton D, Trusolino L, Maughan T, Campbell AD, Loughrey MB, Dunne PD, Tsantoulis P, Huels DJ, Tejpar S, Sansom OJ, Leedham SJ. Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia. Cell Stem Cell. 2022 Nov 3;29(11):1612. doi: 10.1016/j.stem.2022.09.005.

 

Koppens MA*, Davis H*, Valbuena GN, Mulholland EJ, Nasreddin N, Colombe M, Antanaviciute A, Biswas S, Friedrich M, Lee L; Oxford IBD cohort investigators, Wang LM, Koelzer VH, East JE, Simmons A, Winton DJ, Leedham SJ. BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration. Gastroenterology. 2021 Jul;161(1):239-254.e9. doi: 10.1053/j.gastro.2021.03.052. Epub 2021 Apr 2