Taylor group: Translational Genomics
Translation of genetics research into clinical practice
Research overview
Oxford Biomedical Research Centre – Genomic Medicine Theme
Professor Jenny Taylor is Co-Theme Leader of the Genomic Medicine Theme of the Oxford Biomedical Research Centre (BRC), one of several such centres in the UK funded by the National Institute of Health Research with the overarching aim of translating advances in biomedical research into NHS practice.
The aims of the Genomic Medicine Theme are to:
- apply next-generation sequencing technologies (NGS) to the discovery of novel disease genes
- evaluate and develop these technologies for rapid translation into the clinic, resulting in new NHS-based genetics services
- provide genetics and genomics infrastructure (platforms and expertise) to support other translational research projects
Our research is truly multi-disciplinary, integrating researchers and clinicians (particularly those based at the Centre) from a range of medical specialities, with clinical scientists from the diagnostic laboratories, and others, including specialists in health economics, informatics, and ethics.
The activities of the Genomic Medicine Theme are divided into three sub-themes, each with a specific programme of collaborative projects. Members of the Taylor group are involved across all three sub-themes, either running projects of their own or as collaborators in wider programmes.
Clinical applications of sequencing
Our team
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Yesim Kesim
Postdoctoral Researcher
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Peggy Cheung
Executive Assistant and Project Coordinator for the Oxford BRC Genetics Theme
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Prasun Dutta
Senior Bioinformatician
Latest publications
The development of biologically contained Sudan virus as an alternative and safe tool for fundamental filovirus research.
Journal article
Verlinden J. et al, (2026), Emerging microbes & infections, 15
Cephalosporins are potent SARS-CoV-2 main protease inhibitors
Journal article
Muntean D-G. et al, (2026), European Journal of Medicinal Chemistry, 316, 118995 - 118995
CleanCTG: A deep learning model for multi-artefact detection and reconstruction in Cardiotocography
Journal article
Wong S. et al, (2026), Biomedical Signal Processing and Control, 123, 110654 - 110654
TTC7A deficiency: A retrospective international study on treatment and outcomes from the Inborn Errors Working Party of EBMT.
Journal article
Prunotto G. et al, (2026), Journal of human immunity, 2
Transcriptomics of type 1 diabetes progression: a validation study in newly diagnosed patients
Journal article
Suomi T. et al, (2026), Ebiomedicine, 130
Common genetic determinants of dynamic human in vivo immune response to Mycobacterium tuberculosis
Preprint
Zhang P. et al, (2026)
Genomic Epidemiology of Multi-Modal ESBL Gene Transmission among Enterobacterales in a Neonatal Unit
Preprint
Parker MJ. et al, (2026)
A scalable high-throughput serolomics platform for profiling serum antibody responses in large-scale population-based cohorts
Journal article
Kröller L. et al, (2026), Nature Protocols
Dopamine replacement therapy modulates DDC, prolactin and AOC3 levels in Parkinson’s disease
Journal article
van Hillegondsberg L. et al, (2026), npj Parkinson's Disease
VDJ-REMIX: REpertoire Module Identification and eXploration
Journal article
Amin S. et al, (2026), Bioinformatics, 42